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CKD-602, a topoisomerase I inhibitor, induces apoptosis and cell-cycle arrest and inhibits invasion in cervical cancer

BACKGROUND: Cervical cancer is the third most common gynecological malignancy. Conventional treatment options are known to be ineffective for the majority of patients with advanced or recurrent cervical cancer. Therefore, novel therapeutic agents for cervical cancer are necessary. In this study, the...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Lee, Sungha, Ho, Jung Yoon, Liu, Jing Jing, Lee, Hyewon, Park, Jae Young, Baik, Minwha, Ko, Minji, Lee, Seon Ui, Choi, Youn Jin, Hur, Soo Young
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540464/
https://ncbi.nlm.nih.gov/pubmed/31138113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-019-0089-y
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