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Alzheimer’s disease neuropathological change and loss of matrix/neuropil in patients with idiopathic Normal Pressure Hydrocephalus, a model of Alzheimer’s disease

Here, we assessed unique brain tissue samples, obtained from living subjects with idiopathic Normal Pressure Hydrocephalus (iNPH). Our cohort of 95 subjects with age ranging from 75 to 79 years, displayed a high prevalence of β-amyloid (Aβ) and hyperphosphorylated τ (HPτ) pathology (63 and 61%, resp...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Libard, Sylwia, Alafuzoff, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540414/
https://ncbi.nlm.nih.gov/pubmed/31142354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0748-9
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