The hypoxia conditioned mesenchymal stem cells promote hepatocellular carcinoma progression through YAP mediated lipogenesis reprogramming

BACKGROUND: Tumor microenvironment (TME) plays a very important role in cancer progression. The mesenchymal stem cells (MSC), a major compartment of TME, have been shown to promote hepatocellular carcinoma (HCC) progression and metastasis. As hypoxia is a common feature of TME, it is essential to in...

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Опубликовано в: :J Exp Clin Cancer Res
Главные авторы: Liu, Yang, Ren, Haozhen, Zhou, Yuan, Shang, Longcheng, Zhang, Yuheng, Yang, Faji, Shi, Xiaolei
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540399/
https://ncbi.nlm.nih.gov/pubmed/31142342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1219-7
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