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Menaquinone-4 Suppresses Lipopolysaccharide-Induced Inflammation in MG6 Mouse Microglia-Derived Cells by Inhibiting the NF-κB Signaling Pathway

The overactivation of microglia is known to trigger inflammatory reactions in the central nervous system, which ultimately induce neuroinflammatory disorders including Alzheimer’s disease. However, increasing evidence has shown that menaquinone-4 (MK-4), a subtype of vitamin K(2), can attenuate infl...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Saputra, Wahyu Dwi, Aoyama, Nao, Komai, Michio, Shirakawa, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540242/
https://ncbi.nlm.nih.gov/pubmed/31083359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092317
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