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Zinc Attenuates the Cytotoxicity of Some Stimuli by Reducing Endoplasmic Reticulum Stress in Hepatocytes

Zinc is an essential trace element and plays critical roles in cellular integrity and biological functions. Excess copper induced both oxidative stress and endoplasmic reticulum (ER) stress in liver-derived cultured cells. Excess copper also induced impairment of autophagic flux at the step of autop...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Kusanaga, Masashi, Oe, Shinji, Ogino, Noriyoshi, Minami, Sota, Miyagawa, Koichiro, Honma, Yuichi, Harada, Masaru
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540033/
https://ncbi.nlm.nih.gov/pubmed/31058829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092192
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