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Down-Regulation of MHC Class I Expression in Human Keratinocytes Using Viral Vectors Containing US11 Gene of Human Cytomegalovirus and Cultivation on Bovine Collagen-Elastin Matrix (Matriderm(®)): Potential Approach for an Immune-Privileged Skin Substitute

Skin transplantation, especially in burn patients, is still challenging because surgeons are faced with limited disposability of autologous donor side material. The in vitro culture of keratinocytes has become an important reconstructive option. However, only non-immunogenic allogenic keratinocytes...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Schlottmann, Frederik, Strauss, Sarah, Hake, Kevin, Vogt, Peter M., Bucan, Vesna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540026/
https://ncbi.nlm.nih.gov/pubmed/31027326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092056
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