Induction of t(11;14) IgH enhancer/promoter-cyclin D1 gene translocation using CRISPR/Cas9

Chromosomal translocation is a key process in the oncogenic transformation of somatic cells. Previously, artificial induction of chromosomal translocation was performed using homologous recombination-mediated loxP labeling of target regions followed by Cre-mediated recombination. Recent progress in...

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Dades bibliogràfiques
Publicat a:Oncol Lett
Autors principals: Tsuyama, Naohiro, Abe, Yu, Yanagi, Aki, Yanai, Yukari, Sugai, Misaki, Katafuchi, Atsushi, Kawamura, Fumihiko, Kamiya, Kenji, Sakai, Akira
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2019
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6539856/
https://ncbi.nlm.nih.gov/pubmed/31289497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10303
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