Emerging Roles of C-Myc in Cancer Stem Cell-Related Signaling and Resistance to Cancer Chemotherapy: A Potential Therapeutic Target Against Colorectal Cancer

Myc is a nuclear transcription factor that mainly regulates cell growth, cell cycle, metabolism, and survival. Myc family proteins contain c-Myc, n-Myc, and l-Myc. Among them, c-Myc can become a promising therapeutic target molecule in cancer. Cancer stem cells (CSCs) are known to be responsible for...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Elbadawy, Mohamed, Usui, Tatsuya, Yamawaki, Hideyuki, Sasaki, Kazuaki
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6539579/
https://ncbi.nlm.nih.gov/pubmed/31083525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092340
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