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In-Cell Determination of Lactate Dehydrogenase Activity in a Luminal Breast Cancer Model – ex vivo Investigation of Excised Xenograft Tumor Slices Using dDNP Hyperpolarized [1-(13)C]pyruvate

[1-(13)C]pyruvate, the most widely used compound in dissolution-dynamic nuclear polarization (dDNP) magnetic resonance (MR), enables the visualization of lactate dehydrogenase (LDH) activity. This activity had been demonstrated in a wide variety of cancer models, ranging from cultured cells, to xeno...

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Détails bibliographiques
Publié dans:Sensors (Basel)
Auteurs principaux: Adler-Levy, Yael, Nardi-Schreiber, Atara, Harris, Talia, Shaul, David, Uppala, Sivaranjan, Sapir, Gal, Lev-Cohain, Naama, Sosna, Jacob, Goldberg, Shraga Nahum, Gomori, J. Moshe, Katz-Brull, Rachel
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6539471/
https://ncbi.nlm.nih.gov/pubmed/31060334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/s19092089
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