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Activated Fibroblast Program Orchestrates Tumor Initiation and Progression; Molecular Mechanisms and the Associated Therapeutic Strategies

Neoplastic epithelial cells coexist in carcinomas with various non-neoplastic stromal cells, together creating the tumor microenvironment. There is a growing interest in the cross-talk between tumor cells and stromal fibroblasts referred to as carcinoma-associated fibroblasts (CAFs), which are frequ...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Yoshida, Go J., Azuma, Arata, Miura, Yukiko, Orimo, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6539414/
https://ncbi.nlm.nih.gov/pubmed/31067787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092256
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