Evaluating the In Vivo Specificity of [(18)F]UCB-H for the SV2A Protein, Compared with SV2B and SV2C in Rats Using microPET

The synaptic vesicle protein 2 (SV2) is involved in synaptic vesicle trafficking. The SV2A isoform is the most studied and its implication in epilepsy therapy led to the development of the first SV2A PET radiotracer [(18)F]UCB-H. The objective of this study was to evaluate in vivo, using microPET in...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Serrano, Maria Elisa, Becker, Guillaume, Bahri, Mohamed Ali, Seret, Alain, Mestdagh, Nathalie, Mercier, Joël, Mievis, Frédéric, Giacomelli, Fabrice, Lemaire, Christian, Salmon, Eric, Luxen, André, Plenevaux, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538996/
https://ncbi.nlm.nih.gov/pubmed/31052478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24091705
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