Infection-Induced Intestinal Dysbiosis Is Mediated by Macrophage Activation and Nitrate Production

Oral infection of C57BL/6J mice with Toxoplasma gondii results in a marked bacterial dysbiosis and the development of severe pathology in the distal small intestine that is dependent on CD4(+) T cells and interferon gamma (IFN-γ). This dysbiosis and bacterial translocation contribute to the developm...

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Publicado en:mBio
Main Authors: Wang, Shuai, El-Fahmawi, Ayah, Christian, David A., Fang, Qun, Radaelli, Enrico, Chen, Longfei, Sullivan, Megan C., Misic, Ana M., Ellringer, Jodi A., Zhu, Xing-Quan, Winter, Sebastian E., Hunter, Christopher A., Beiting, Daniel P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538788/
https://ncbi.nlm.nih.gov/pubmed/31138751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00935-19
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