Efficacy of Oral Encochleated Amphotericin B in a Mouse Model of Cryptococcal Meningoencephalitis

Cryptococcus neoformans is an encapsulated yeast responsible for approximately a quarter of a million deaths worldwide annually despite therapy, and upwards of 11% of HIV/AIDS-related deaths, rivaling the impact of tuberculosis and malaria. However, the most effective antifungal agent, amphotericin...

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Publicado en:mBio
Main Authors: Lu, R., Hollingsworth, C., Qiu, J., Wang, A., Hughes, E., Xin, X., Konrath, K. M., Elsegeiny, W., Park, Yoon-Dong, Atakulu, L., Craft, J. C., Tramont, E. C., Mannino, R., Williamson, P. R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538785/
https://ncbi.nlm.nih.gov/pubmed/31138748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00724-19
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