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Single-cell RNA sequencing identifies TGF-β as a key regenerative cue following LPS-induced lung injury

Many lung diseases result from a failure of efficient regeneration of damaged alveolar epithelial cells (AECs) after lung injury. During regeneration, AEC2s proliferate to replace lost cells, after which proliferation halts and some AEC2s transdifferentiate into AEC1s to restore normal alveolar stru...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:JCI Insight
Main Authors: Riemondy, Kent A., Jansing, Nicole L., Jiang, Peng, Redente, Elizabeth F., Gillen, Austin E., Fu, Rui, Miller, Alyssa J., Spence, Jason R., Gerber, Anthony N., Hesselberth, Jay R., Zemans, Rachel L.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538357/
https://ncbi.nlm.nih.gov/pubmed/30913038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123637
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