Composite biomaterial repair strategy to restore biomechanical function and reduce herniation risk in an ex vivo large animal model of intervertebral disc herniation with varying injury severity

Back pain commonly arises from intervertebral disc (IVD) damage including annulus fibrosus (AF) defects and nucleus pulposus (NP) loss. Poor IVD healing motivates developing tissue engineering repair strategies. This study evaluated a composite injectable IVD biomaterial repair strategy using carbox...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hom, Warren W., Tschopp, Melanie, Lin, Huizi A., Nasser, Philip, Laudier, Damien M., Hecht, Andrew C., Nicoll, Steven B., Iatridis, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538241/
https://ncbi.nlm.nih.gov/pubmed/31136604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217357
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