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MicroRNA26 attenuates vascular smooth muscle maturation via endothelial BMP signalling

As small regulatory transcripts, microRNAs (miRs) act as genetic ‘fine tuners’ of posttranscriptional events, and as genetic switches to promote phenotypic switching. The miR miR26a targets the BMP signalling effector, smad1. We show that loss of miR26a leads to hemorrhage (a loss of vascular stabil...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Genet
Prif Awduron: Watterston, Charlene, Zeng, Lei, Onabadejo, Abidemi, Childs, Sarah J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538191/
https://ncbi.nlm.nih.gov/pubmed/31091229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008163
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