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MicroRNA26 attenuates vascular smooth muscle maturation via endothelial BMP signalling

As small regulatory transcripts, microRNAs (miRs) act as genetic ‘fine tuners’ of posttranscriptional events, and as genetic switches to promote phenotypic switching. The miR miR26a targets the BMP signalling effector, smad1. We show that loss of miR26a leads to hemorrhage (a loss of vascular stabil...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Watterston, Charlene, Zeng, Lei, Onabadejo, Abidemi, Childs, Sarah J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538191/
https://ncbi.nlm.nih.gov/pubmed/31091229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008163
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