Mechanistic analyses in kidney transplant recipients prospectively randomized to two steroid free regimen—Low dose Tacrolimus with Everolimus versus standard dose Tacrolimus with Mycophenolate Mofetil

Calcineurin inhibitors (CNI), the cornerstone of immunosuppression after transplantation are implicated in nephrotoxicity and allograft dysfunction. We hypothesized that combined low doses of CNI and Everolimus (EVR) may result in better graft outcomes and greater tolerogenic milieu. Forty adult ren...

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Udgivet i:PLoS One
Main Authors: Traitanon, Opas, Mathew, James M., Shetty, Aneesha, Bontha, Sai Vineela, Maluf, Daniel G., El Kassis, Yvonne, Park, Sook H., Han, Jing, Ansari, M. Javeed, Leventhal, Joseph R., Mas, Valeria, Gallon, Lorenzo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538151/
https://ncbi.nlm.nih.gov/pubmed/31136582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216300
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