Pharmacodynamic study of radium-223 in men with bone metastatic castration resistant prostate cancer

BACKGROUND: Radium-223 is a targeted alpha-particle therapy that improves survival in men with metastatic castration resistant prostate cancer (mCRPC), particularly in men with elevated serum levels of bone alkaline phosphatase (B-ALP). We hypothesized that osteomimicry, a form of epithelial plastic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Armstrong, Andrew J., Gupta, Santosh, Healy, Patrick, Kemeny, Gabor, Leith, Beth, Zalutsky, Michael R., Spritzer, Charles, Davies, Catrin, Rothwell, Colin, Ware, Kathryn, Somarelli, Jason A., Wood, Kris, Ribar, Thomas, Giannakakou, Paraskevi, Zhang, Jiaren, Gerber, Drew, Anand, Monika, Foo, Wen-Chi, Halabi, Susan, Gregory, Simon G., George, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538141/
https://ncbi.nlm.nih.gov/pubmed/31136607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216934
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