Pharmacodynamic study of radium-223 in men with bone metastatic castration resistant prostate cancer

BACKGROUND: Radium-223 is a targeted alpha-particle therapy that improves survival in men with metastatic castration resistant prostate cancer (mCRPC), particularly in men with elevated serum levels of bone alkaline phosphatase (B-ALP). We hypothesized that osteomimicry, a form of epithelial plastic...

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Publicat a:PLoS One
Autors principals: Armstrong, Andrew J., Gupta, Santosh, Healy, Patrick, Kemeny, Gabor, Leith, Beth, Zalutsky, Michael R., Spritzer, Charles, Davies, Catrin, Rothwell, Colin, Ware, Kathryn, Somarelli, Jason A., Wood, Kris, Ribar, Thomas, Giannakakou, Paraskevi, Zhang, Jiaren, Gerber, Drew, Anand, Monika, Foo, Wen-Chi, Halabi, Susan, Gregory, Simon G., George, Daniel J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538141/
https://ncbi.nlm.nih.gov/pubmed/31136607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216934
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