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Acid-Sensing Ion Channel 1a Is Involved in N-Methyl D-Aspartate Receptor-Dependent Long-Term Depression in the Hippocampus

Acid-sensing ion channels (ASICs), members of the degenerin/epithelial Na(+) channel superfamily, are largely expressed in the mammalian nervous system. ASIC1a is highly permeable to Ca(2+) and are involved in many physiological processes, including synaptic plasticity, learning, and memory. To clar...

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Pubblicato in:Front Pharmacol
Autori principali: Mango, D., Nisticò, R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537656/
https://ncbi.nlm.nih.gov/pubmed/31178731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00555
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