Is Visible Aminolevulinic Acid-Induced Fluorescence an Independent Biomarker for Prognosis in Histologically Confirmed (World Health Organization 2016) Low-Grade Gliomas?

BACKGROUND: Approximately 20% of low-grade gliomas (LGG) display visible protoporphyrin fluorescence during surgery after 5-aminolevulinic acid (5-ALA) administration. OBJECTIVE: To determine if fluorescence represents a prognostic marker in LGG. METHODS: Seventy-four consecutive patients with LGG (...

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Bibliographic Details
Published in:Neurosurgery
Main Authors: Jaber, Mohammed, Ewelt, Christian, Wölfer, Johannes, Brokinkel, Benjamin, Thomas, Christian, Hasselblatt, Martin, Grauer, Oliver, Stummer, Walter
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Research—Human—Clinical Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537633/
https://ncbi.nlm.nih.gov/pubmed/30107580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuros/nyy365
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