Mutagen resistance and mutation restriction of St. Louis encephalitis virus

The error rate of the RNA-dependent RNA polymerase (RdRp) of RNA viruses is important in maintaining genetic diversity for viral adaptation and fitness. Numerous studies have shown that mutagen-resistant RNA virus variants display amino acid mutations in the RdRp and other replicase subunits, which...

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Bibliografiske detaljer
Udgivet i:J Gen Virol
Main Authors: Griesemer, Sara B, Kramer, Laura D, Van Slyke, Greta A, Pata, Janice D, Gohara, David W, Cameron, Craig E, Ciota, Alexander T
Format: Artigo
Sprog:Inglês
Udgivet: Microbiology Society 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537618/
https://ncbi.nlm.nih.gov/pubmed/28284278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000682
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