The impact of At1r inhibition via losartan on the anti-leukaemic effects of doxorubicin in acute myeloid leukaemia

INTRODUCTION: Bone marrow renin–angiotensin system(RAS) modulates acute myeloid leukaemia(AML).The aim of this study is to clarify the relationships between RAS and AML, and to show the effect of losartan and doxorubicin treatment in AML cell lines. METHODS: AML cell lines including CESS, HL-60, MO-...

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Bibliografske podrobnosti
izdano v:J Renin Angiotensin Aldosterone Syst
Main Authors: Ghasemi, Mehdi, Okay, Mufide, Turk, Seyhan, Naeemaee, Ronak, Guver, Ebru, Malkan, Umit Y, Aksu, Salih, Sayinalp, Nilgun, Haznedaroglu, Ibrahim C
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2019
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537254/
https://ncbi.nlm.nih.gov/pubmed/31117912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1470320319851310
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