The impact of At1r inhibition via losartan on the anti-leukaemic effects of doxorubicin in acute myeloid leukaemia

INTRODUCTION: Bone marrow renin–angiotensin system(RAS) modulates acute myeloid leukaemia(AML).The aim of this study is to clarify the relationships between RAS and AML, and to show the effect of losartan and doxorubicin treatment in AML cell lines. METHODS: AML cell lines including CESS, HL-60, MO-...

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Detalhes bibliográficos
Publicado no:J Renin Angiotensin Aldosterone Syst
Main Authors: Ghasemi, Mehdi, Okay, Mufide, Turk, Seyhan, Naeemaee, Ronak, Guver, Ebru, Malkan, Umit Y, Aksu, Salih, Sayinalp, Nilgun, Haznedaroglu, Ibrahim C
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537254/
https://ncbi.nlm.nih.gov/pubmed/31117912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1470320319851310
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