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PRIMMO study protocol: a phase II study combining PD-1 blockade, radiation and immunomodulation to tackle cervical and uterine cancer

BACKGROUND: Immunotherapeutic approaches have revolutionized oncological practice but are less evaluated in gynecological malignancies. PD-1/PD-L1 blockade in gynecological cancers showed objective responses in 13–17% of patients. This could be due to immunosuppressive effects exerted by gynecologic...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Tuyaerts, Sandra, Van Nuffel, An M. T., Naert, Eline, Van Dam, Peter A., Vuylsteke, Peter, De Caluwé, Alex, Aspeslagh, Sandrine, Dirix, Piet, Lippens, Lien, De Jaeghere, Emiel, Amant, Frédéric, Vandecasteele, Katrien, Denys, Hannelore
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537207/
https://ncbi.nlm.nih.gov/pubmed/31138229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5676-3
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