Protein arginine methyltransferase 5: A novel therapeutic target for triple‐negative breast cancers

TNBC is a highly heterogeneous and aggressive breast cancer subtype associated with high relapse rates, and for which no targeted therapy yet exists. Protein arginine methyltransferase 5 (PRMT5), an enzyme which catalyzes the methylation of arginines on histone and non‐histone proteins, has recently...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Vinet, Mathilde, Suresh, Samyuktha, Maire, Virginie, Monchecourt, Clarisse, Némati, Fariba, Lesage, Laetitia, Pierre, Fabienne, Ye, Mengliang, Lescure, Auriane, Brisson, Amélie, Meseure, Didier, Nicolas, André, Rigaill, Guillem, Marangoni, Elisabetta, Del Nery, Elaine, Roman‐Roman, Sergio, Dubois, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537044/
https://ncbi.nlm.nih.gov/pubmed/30957988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2114
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