Association of LRP1B Mutation With Tumor Mutation Burden and Outcomes in Melanoma and Non-small Cell Lung Cancer Patients Treated With Immune Check-Point Blockades

Background: Tumor mutation burden (TMB) have been served as the most prevalent biomarkers to predict immunotherapy response. LRP1B (low-density lipoprotein receptor-related protein 1B) is frequently mutated in melanoma, non-small cell lung cancer (NSCLC) and other tumors; however, its association wi...

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Опубликовано в: :Front Immunol
Главные авторы: Chen, Hao, Chong, Wei, Wu, Qian, Yao, Yueliang, Mao, Min, Wang, Xin
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536574/
https://ncbi.nlm.nih.gov/pubmed/31164891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01113
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