BD-2 and BD-3 increase skin flap survival in a model of ischemia and Pseudomonas aeruginosa infection

The main aim of this work was to study the usefulness of human β-defensins 2 (BD-2) and 3 (BD-3), which are part of the innate immune system, in the treatment of infected ischemic skin flaps. We investigated the effect of transducing rat ischemic skin flaps with lentiviral vectors encoding human BD-...

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Vydáno v:Sci Rep
Hlavní autoři: Casal, Diogo, Iria, Inês, Ramalho, José S., Alves, Sara, Mota-Silva, Eduarda, Mascarenhas-Lemos, Luís, Pontinha, Carlos, Guadalupe-Cabral, Maria, Ferreira-Silva, José, Ferraz-Oliveira, Mário, Vassilenko, Valentina, Goyri-O’Neill, João, Pais, Diogo, Videira, Paula A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536547/
https://ncbi.nlm.nih.gov/pubmed/31133641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44153-y
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