Engineered Heart Slice Model of Arrhythmogenic Cardiomyopathy Using Plakophilin-2 Mutant Myocytes

Arrhythmogenic cardiomyopathy (AC), a cause of sudden cardiac death among young and otherwise healthy individuals, is a heritable disease that can be modeled in vitro using patient-specific cardiac myocytes (CMs) from induced pluripotent stem cells. An understanding of underlying disease mechanisms,...

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Publicado en:Tissue Eng Part A
Autores principales: Blazeski, Adriana, Lowenthal, Justin, Wang, Yin, Teuben, Roald, Zhu, Renjun, Gerecht, Sharon, Tomaselli, Gordon, Tung, Leslie
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Special Issue Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535962/
https://ncbi.nlm.nih.gov/pubmed/30520705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2018.0272
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