HEATR1 modulates cell survival in non-small cell lung cancer via activation of the p53/PUMA signaling pathway

Aim: To determine the mechanisms of HEATR1 on cell survival in non-small cell lung cancer (NSCLC). Methods: HEATR1 mRNA expression levels in 57 pairs of NSCLC tumor and adjacent normal lung tissues were analyzed using the TCGA database. The effect of HEATR1 inhibition on cell proliferation, apoptosi...

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Vydáno v:Onco Targets Ther
Hlavní autoři: He, Saifei, Ma, Xing, Ye, Ying, Zhang, Miao, Zhuang, Juhua, Song, Yanan, Xia, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535672/
https://ncbi.nlm.nih.gov/pubmed/31190896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S195826
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