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High-Resolution Melting Assay for Genotyping Variants of the CYP2C19 Enzyme and Predicting Voriconazole Effectiveness

Voriconazole is a triazole antifungal agent recommended as primary treatment for invasive aspergillosis, as well as some other mold infections. However, it presents some pharmacokinetic singularities that lead to a great variability intra- and interindividually, nonlinear pharmacokinetics, and a nar...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bernal-Martínez, L., Alcazar Fuoli, L., Miguel-Revilla, B., Carvalho, A., Cuétara Garcia, M. S., Garcia-Rodriguez, J., Cunha, C., Gómez-García de la Pedrosa, E., Gomez-Lopez, A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535561/
https://ncbi.nlm.nih.gov/pubmed/30910893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02399-18
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