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A Novel, Widespread qacA Allele Results in Reduced Chlorhexidine Susceptibility in Staphylococcus epidermidis

Chlorhexidine gluconate (CHG) is a topical antiseptic widely used in health care settings. In Staphylococcus spp., the pump QacA effluxes CHG, while the closely related QacB cannot due to a single amino acid substitution. We characterized 1,050 cutaneous Staphylococcus isolates obtained from 173 ped...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Addetia, Amin, Greninger, Alexander L., Adler, Amanda, Yuan, Shuhua, Makhsous, Negar, Qin, Xuan, Zerr, Danielle M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535555/
https://ncbi.nlm.nih.gov/pubmed/30988144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02607-18
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