Novel MenA Inhibitors Are Bactericidal against Mycobacterium tuberculosis and Synergize with Electron Transport Chain Inhibitors

Mycobacterium tuberculosis is the leading cause of morbidity and death resulting from infectious disease worldwide. The incredible disease burden, combined with the long course of drug treatment and an increasing incidence of antimicrobial resistance among M. tuberculosis isolates, necessitates nove...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Berube, Bryan J., Russell, Dara, Castro, Lina, Choi, Seoung-ryoung, Narayanasamy, Prabagaran, Parish, Tanya
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535543/
https://ncbi.nlm.nih.gov/pubmed/30962346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02661-18
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