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Trps1 transcription factor regulates mineralization of dental tissues and proliferation of tooth organ cells

Mutations of the TRPS1 gene cause trichorhinophalangeal syndrome (TRPS), a skeletal dysplasia with dental abnormalities. TRPS dental phenotypes suggest that TRPS1 regulates multiple aspects of odontogenesis, including the tooth number and size. Previous studies delineating Trps1 expression throughou...

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Detalhes bibliográficos
Publicado no:Mol Genet Metab
Main Authors: Goss, Morgan, Socorro, Mairobys, Monier, Daisy, Verdelis, Kostas, Napierala, Dobrawa
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535116/
https://ncbi.nlm.nih.gov/pubmed/30691926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2019.01.014
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