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Five miRNAs-mediated PIEZO2 downregulation, accompanied with activation of Hedgehog signaling pathway, predicts poor prognosis of breast cancer

Roles of Piezo-type mechanosensitive ion channel component 2 (PIEZO2) in cancer remain largely unknown. Herein, we explored PIEZO2 expression, prognosis and underlying mechanisms in cancer. Breast was selected as the candidate as its relatively higher expression level of PIEZO2 than other human tiss...

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Bibliographic Details
Published in:Aging (Albany NY)
Main Authors: Lou, Weiyang, Liu, Jingxing, Ding, Bisha, Jin, Luqi, Xu, Liang, Li, Xia, Chen, Jing, Fan, Weimin
Format: Artigo
Language:Inglês
Published: Impact Journals 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535055/
https://ncbi.nlm.nih.gov/pubmed/31058608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101934
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