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Extrinsic conditions influence the self-association and structure of IF(1), the regulatory protein of mitochondrial ATP synthase

The endogenous inhibitor of ATP synthase in mitochondria, called IF(1), conserves cellular energy when the proton-motive force collapses by inhibiting ATP hydrolysis. Around neutrality, the 84-amino-acid bovine IF(1) is thought to self-assemble into active dimers and, under alkaline conditions, into...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Boreikaite, Vytaute, Wicky, Basile I. M., Watt, Ian N., Clarke, Jane, Walker, John E.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535023/
https://ncbi.nlm.nih.gov/pubmed/31064873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903535116
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