Extracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis

Extracellular vesicles (EVs) are emerging as potent mediators of intercellular communication with roles in inflammation and disease. In this study, we examined the role of EVs from blood plasma (pEVs) in an experimental autoimmune encephalomyelitis mouse model of central nervous system demyelination...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Willis, Cory M., Nicaise, Alexandra M., Menoret, Antoine, Ryu, Jae Kyu, Mendiola, Andrew S., Jellison, Evan R., Givogri, Maria I., Han, David K., Bongarzone, Ernesto R., Akassoglou, Katerina, Vella, Anthony T., Crocker, Stephen J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2019
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535008/
https://ncbi.nlm.nih.gov/pubmed/31068461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816911116
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