Strong CD8+ lymphocyte infiltration in combination with expression of HLA class I is associated with better tumor control in breast cancer patients treated with neoadjuvant chemotherapy

PURPOSE: Tumor-infiltrating lymphocytes (TILs) are associated with pathological complete response (pCR) and survival after neoadjuvant chemotherapy (NAC) in patients with early breast cancer. We investigated the prognostic and predictive role of TILs, macrophages, and HLA class 1 expression after NA...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: de Groot, A. F., Blok, E. J., Charehbili, A., Engels, C. C., Smit, V. T. H. B. M., Dekker-Ensink, N. G., Putter, H., Meershoek-Klein Kranenbarg, E., van de Velde, C. J. H., Liefers, G. J., Nortier, J. W. R., Kuppen, P. J. K., van der Burg, S. H., Kroep, J. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
Assuntos:
Clinical Trial
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534526/
https://ncbi.nlm.nih.gov/pubmed/30868392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-019-05195-y
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