Down‐titration and discontinuation strategies of tumour necrosis factor–blocking agents for rheumatoid arthritis in patients with low disease activity

BACKGROUND: Anti–tumour necrosis factor (TNF) agents are effective in treating people with rheumatoid arthritis (RA), but are associated with (dose‐dependent) adverse effects and high costs. To prevent overtreatment, several trials have assessed the effectiveness of down‐titration compared with cont...

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Udgivet i:Cochrane Database Syst Rev
Main Authors: Verhoef, Lise M, van den Bemt, Bart JF, van der Maas, Aatke, Vriezekolk, Johanna E, Hulscher, Marlies E, van den Hoogen, Frank HJ, Jacobs, Wilco CH, van Herwaarden, Noortje, den Broeder, Alfons A
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2019
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534285/
https://ncbi.nlm.nih.gov/pubmed/31125448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/14651858.CD010455.pub3
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