Endocytosis Deficient Murine Xcl1-Fusion Vaccine Enhances Protective Antibody Responses in Mice

Targeting antigen to surface receptors on dendritic cells (DCs) can improve antibody response against subunit vaccines. We have previously observed that human XCL1-fusion vaccines target murine Xcr1(+) DCs without actively inducing endocytosis of the antigen, resulting in enhanced antibody responses...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Gudjonsson, Arnar, Andersen, Tor Kristian, Sundvold-Gjerstad, Vibeke, Bogen, Bjarne, Fossum, Even
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533920/
https://ncbi.nlm.nih.gov/pubmed/31156636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01086
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