Statins significantly reduce mortality in patients receiving clopidogrel without affecting platelet activation and aggregation: a systematic review and meta-analysis

BACKGROUND: Combination of statins and clopidogrel is frequently administered in patients with coronary artery disease (CAD). They are mainly activated and eliminated in the liver by cytochrome P450 isoenzyme 3A4 (CYP3A4). The aim was to clarify whether the coadministration of clopidogrel and statin...

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Bibliografiske detaljer
Udgivet i:Lipids Health Dis
Main Authors: An, Ke, Huang, Rong, Tian, Sai, Guo, Dan, Wang, Jiaqi, Lin, Hongyan, Wang, Shaohua
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533696/
https://ncbi.nlm.nih.gov/pubmed/31122249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-019-1053-0
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