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What Your Crystal Structure Will Not Tell You about Enzyme Function
[Image: see text] Enzyme function requires that enzyme structures be dynamic. Substrate binding, product release, and transition state stabilization typically involve different enzyme conformers. Furthermore, in multistep enzyme-catalyzed reactions, more than one enzyme conformation may be important...
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| Publicado no: | Acc Chem Res |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2019
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6533606/ https://ncbi.nlm.nih.gov/pubmed/31034199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.9b00066 |
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