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Isorhamnetin attenuates osteoarthritis by inhibiting osteoclastogenesis and protecting chondrocytes through modulating reactive oxygen species homeostasis

Increasing evidence indicates that osteoarthritis (OA) is a musculoskeletal disease affecting the whole joint, including both cartilage and subchondral bone. Reactive oxygen species (ROS) have been demonstrated to be one of the important destructive factors during early‐stage OA development. The obj...

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Библиографические подробности
Опубликовано в: :J Cell Mol Med
Главные авторы: Zhou, Feng, Mei, Jingtian, Yuan, Kai, Han, Xiuguo, Qiao, Han, Tang, Tingting
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533508/
https://ncbi.nlm.nih.gov/pubmed/30983153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14333
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