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Diversity of dermal fibroblasts as major determinant of variability in cell reprogramming

Induced pluripotent stem cells (iPSCs) are adult somatic cells genetically reprogrammed to an embryonic stem cell‐like state. Notwithstanding their autologous origin and their potential to differentiate towards cells of all three germ layers, iPSC reprogramming is still affected by low efficiency. A...

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Détails bibliographiques
Publié dans:J Cell Mol Med
Auteurs principaux: Sacco, Anna Maria, Belviso, Immacolata, Romano, Veronica, Carfora, Antonia, Schonauer, Fabrizio, Nurzynska, Daria, Montagnani, Stefania, Di Meglio, Franca, Castaldo, Clotilde
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533477/
https://ncbi.nlm.nih.gov/pubmed/30980516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14316
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