Therapeutic efficacy of anti‐MMP9 antibody in combination with nab‐paclitaxel‐based chemotherapy in pre‐clinical models of pancreatic cancer

Matrix metalloproteinase 9 (MMP9) is involved in the proteolysis of extracellular proteins and plays a critical role in pancreatic ductal adenocarcinoma (PDAC) progression, invasion and metastasis. The therapeutic potential of an anti‐MMP9 antibody (αMMP9) was evaluated in combination with nab‐pacli...

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Detaylı Bibliyografya
Yayımlandı:J Cell Mol Med
Asıl Yazarlar: Awasthi, Niranjan, Mikels‐Vigdal, Amanda J., Stefanutti, Erin, Schwarz, Margaret A., Monahan, Sheena, Smith, Victoria, Schwarz, Roderich E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533474/
https://ncbi.nlm.nih.gov/pubmed/30941918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14242
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