Nicotinamide phosphoribosyltransferase is a molecular target of potent anticancer agents identified from phenotype-based drug screening

Phenotypic screening in drug discovery has been revived with the expectation of providing promising lead compounds and drug targets and improving the success rate of drug approval. However, target identification remains a major bottleneck in phenotype-based drug discovery. We identified the lead com...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Yamaguchi, Daisuke, Imaizumi, Takamichi, Yagi, Kaori, Matsumoto, Yuichi, Nakashima, Takayuki, Hirose, Akiyo, Kashima, Naomi, Nosaka, Yukino, Hamada, Tomoko, Okawa, Katsuya, Nishiya, Yoichi, Kubo, Kazuo
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6533267/
https://ncbi.nlm.nih.gov/pubmed/31123329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43994-x
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