The R2TP complex regulates paramyxovirus RNA synthesis

The regulation of paramyxovirus RNA synthesis by host proteins is poorly understood. Here, we identified a novel regulation mechanism of paramyxovirus RNA synthesis by the Hsp90 co-chaperone R2TP complex. We showed that the R2TP complex interacted with the paramyxovirus polymerase L protein and that...

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Vydáno v:PLoS Pathog
Hlavní autoři: Katoh, Hiroshi, Sekizuka, Tsuyoshi, Nakatsu, Yuichiro, Nakagawa, Reiko, Nao, Naganori, Sakata, Masafumi, Kato, Fumihiro, Kuroda, Makoto, Kidokoro, Minoru, Takeda, Makoto
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532945/
https://ncbi.nlm.nih.gov/pubmed/31121004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007749
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