The R2TP complex regulates paramyxovirus RNA synthesis

The regulation of paramyxovirus RNA synthesis by host proteins is poorly understood. Here, we identified a novel regulation mechanism of paramyxovirus RNA synthesis by the Hsp90 co-chaperone R2TP complex. We showed that the R2TP complex interacted with the paramyxovirus polymerase L protein and that...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: Katoh, Hiroshi, Sekizuka, Tsuyoshi, Nakatsu, Yuichiro, Nakagawa, Reiko, Nao, Naganori, Sakata, Masafumi, Kato, Fumihiro, Kuroda, Makoto, Kidokoro, Minoru, Takeda, Makoto
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532945/
https://ncbi.nlm.nih.gov/pubmed/31121004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007749
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