Heme Oxygenase-1 Promoter Polymorphisms and Risk of Spina Bifida

BACKGROUND: Spina bifida is the most common form of neural tube defects (NTDs). Etiologies of NTDs are multifactorial, and oxidative stress is believed to play a key role in NTD development. Heme oxygenase (HO), the rate-limiting enzyme in heme degradation, has multiple protective properties includi...

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Bibliographic Details
Published in:Birth Defects Res A Clin Mol Teratol
Main Authors: Fujioka, Kazumichi, Yang, Wei, Wallenstein, Matthew B., Zhao, Hui, Wong, Ronald J., Stevenson, David K., Shaw, Gary M.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532789/
https://ncbi.nlm.nih.gov/pubmed/26173399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23343
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