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Simplified immunosuppressive and neuroprotective agents based on gracilin A

The architecture and bioactivity of natural products frequently serves as an embarkation point for exploration of biologically-relevant chemical space. Total synthesis followed by derivative synthesis has historically enabled a deeper understanding of structure-activity relationships. However, synth...

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Detalhes bibliográficos
Publicado no:Nat Chem
Main Authors: Abbasov, Mikail E., Alvariño, Rebeca, Chaheine, Christian M., Alonso, Eva, Sánchez, Jon A., Conner, Michael L., Alfonso, Amparo, Jaspars, Marcel, Botana, Luis M., Romo, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532426/
https://ncbi.nlm.nih.gov/pubmed/30903037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-019-0230-0
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