Tetrahydrocurcumin Ameliorates Diabetic Cardiomyopathy by Attenuating High Glucose-Induced Oxidative Stress and Fibrosis via Activating the SIRT1 Pathway

Hyperglycemia-induced oxidative stress and fibrosis play a crucial role in the development of diabetic cardiomyopathy (DCM). Tetrahydrocurcumin (THC), a major bioactive metabolite of natural antioxidant curcumin, is reported to exert even more effective antioxidative and superior antifibrotic proper...

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Pubblicato in:Oxid Med Cell Longev
Autori principali: Li, Kaifeng, Zhai, Mengen, Jiang, Liqing, Song, Fan, Zhang, Bin, Li, Jie, Li, Hua, Li, Buying, Xia, Lin, Xu, Lu, Cao, Yu, He, Mengshan, Zhu, Hanzhao, Zhang, Liyun, Liang, Hongliang, Jin, Zhenxiao, Duan, Weixun, Wang, Siwang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532281/
https://ncbi.nlm.nih.gov/pubmed/31210844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6746907
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