Integrated high-throughput analysis identifies super enhancers associated with chemoresistance in SCLC

BACKGROUND: Chemoresistance is a primary clinical challenge for the management of small cell lung cancer. Additionally, transcriptional regulation by super enhancer (SE) has an important role in tumor evolution. The functions of SEs, a key class of noncoding DNA cis-regulatory elements, have been th...

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Publicat a:BMC Med Genomics
Autors principals: Bao, Jiarong, Li, Man, Liang, Shumei, Yang, Yunchu, Wu, Jingfang, Zou, Qingqing, Fang, Shun, Chen, Size, Guo, Linlang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532255/
https://ncbi.nlm.nih.gov/pubmed/31118037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0520-9
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