Reactive oxygen species-dependent mitochondrial dynamics and autophagy confer protective effects in retinal pigment epithelial cells against sodium iodate-induced cell death

BACKGROUND: Oxidative stress is a major factor in retinal pigment epithelium (RPE) cells injury that contributes to age-related macular degeneration (AMD). NaIO3 is an oxidative toxic agent and its selective RPE cell damage makes it as a reproducible model of AMD. Although NaIO3 is an oxidative stre...

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Bibliographische Detailangaben
Veröffentlicht in:J Biomed Sci
Hauptverfasser: Chan, Chi-Ming, Huang, Duen-Yi, Sekar, Ponarulselvam, Hsu, Shu-Hao, Lin, Wan-Wan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532221/
https://ncbi.nlm.nih.gov/pubmed/31118030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-019-0531-z
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